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Von Graefe's sign : ウィキペディア英語版
Von Graefe's sign
Von Graefe's sign is the lagging of the upper eyelid on downward rotation of the eye, indicating exophthalmic goiter (Graves' Disease).〔Cline D; Hofstetter HW; Griffin JR. ''Dictionary of Visual Science''. 4th ed. Butterworth-Heinemann, Boston 1997. ISBN 0-7506-9895-0〕 It is a dynamic sign, whereas lid lag is a static sign which may also be present in cicatricial eyelid retraction or congenital ptosis.
A pseudo Graefe's sign (pseudo lid lag) shows a similar lag, but is due to aberrant regeneration of fibres of the oculomotor nerve (III) into the elevator of the upper lid.〔(Definition: pseudo-Graefe sign from Online Medical Dictionary )〕 It occurs in paramyotonia congenita.
A pseudo Graefe's sign is most commonly manifested in just one eye but can occasionally be observed in both. The reason only one eye is affected is not yet clear.
==See also==

*Albrecht von Gräfe
*Boston's sign
*Griffith's sign
*Graves orbitopathy
*Hyperthyroidism, as lid lag may be in hyperthyroid patients lacking Graves' disease.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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